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http://purl.uniprot.org/citations/10097140http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10097140http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10097140http://www.w3.org/2000/01/rdf-schema#comment"Alterations of human chromosome 8p occur frequently in many tumors. We identified a 1.5-Mb common region of allelic loss on 8p22 by allelotype analysis. cDNA selection allowed isolation of several genes, including FEZ1. The predicted Fez1 protein contained a leucine-zipper region with similarity to the DNA-binding domain of the cAMP-responsive activating-transcription factor 5. RNA blot analysis revealed that FEZ1 gene expression was undetectable in more than 60% of epithelial tumors. Mutations were found in primary esophageal cancers and in a prostate cancer cell line. Transcript analysis from several FEZ1-expressing tumors revealed truncated mRNAs, including a frameshift. Alteration and inactivation of the FEZ1 gene may play a role in various human tumors."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.org/dc/terms/identifier"doi:10.1073/pnas.96.7.3928"xsd:string
http://purl.uniprot.org/citations/10097140http://purl.org/dc/terms/identifier"doi:10.1073/pnas.96.7.3928"xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Inoue H."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Inoue H."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Numata S."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Numata S."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Mori M."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Mori M."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Croce C.M."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Croce C.M."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Alder H."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Alder H."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Fidanza V."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Fidanza V."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Murakumo Y."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Murakumo Y."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Baffa R."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Baffa R."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Rattan S."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Rattan S."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Ishii H."xsd:string
http://purl.uniprot.org/citations/10097140http://purl.uniprot.org/core/author"Ishii H."xsd:string