| http://purl.uniprot.org/citations/10197531 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10197531 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10197531 | http://www.w3.org/2000/01/rdf-schema#comment | "Transmembrane ephrinB proteins have important functions during embryonic patterning as ligands for Eph receptor tyrosine kinases and presumably as signal-transducing receptor-like molecules. Consistent with "reverse" signaling, ephrinB1 is localized in sphingo-lipid/cholesterol-enriched raft microdomains, platforms for the localized concentration and activation of signaling molecules. Glutamate receptor-interacting protein (GRIP) and a highly related protein, which we have termed GRIP2, are recruited into these rafts through association with the C-terminal PDZ target site of ephrinB1. Stimulation of ephrinB1 with soluble EphB2 receptor ectodomain causes the formation of large raft patches that also contain GRIP proteins. Moreover, a GRIP-associated serine/threonine kinase activity is recruited into ephrinB1-GRIP complexes. Our findings suggest that GRIP proteins provide a scaffold for the assembly of a multiprotein signaling complex downstream of ephrinB ligands."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(00)80706-0"xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(00)80706-0"xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/author | "Klein R."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/author | "Klein R."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/author | "Seeburg P.H."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/author | "Seeburg P.H."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/author | "Brueckner K."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/author | "Brueckner K."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/author | "Scheiffele P."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/author | "Scheiffele P."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/author | "Herb A."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/author | "Herb A."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/author | "Pablo Labrador J."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/author | "Pablo Labrador J."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/pages | "511-524"xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/pages | "511-524"xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/title | "EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains."xsd:string |
| http://purl.uniprot.org/citations/10197531 | http://purl.uniprot.org/core/title | "EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains."xsd:string |