| http://purl.uniprot.org/citations/10204397 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10204397 | http://www.w3.org/2000/01/rdf-schema#comment | "Cells in developing embryos behave according to their positions in the organism, and therefore seem to be receiving 'positional information'. A widespread view of the mechanism for this is that each cell responds locally to the concentration level of some extracellular chemical which is distributed in a spatial gradient. For molecules conveying and receiving the positional signal, concentrations are likely to be low enough that, per individual cell, only a few thousand molecules may be involved. Fluctuations to be expected in these numbers (Poisson distribution) could readily lead to errors up to a few percent of embryo length in the reading of position. This is an intolerable level of error for some developmental pattern-forming events. Embryos must have means of suppressing such errors. We maintain that this requires communication between cells, and illustrate this by using the reaction part of two well-known Turing-type reaction-diffusion models as the local gradient reader. We show that switching on diffusion in these models leads to adequate suppression of positional errors."xsd:string |
| http://purl.uniprot.org/citations/10204397 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0025-5564(98)10070-6"xsd:string |
| http://purl.uniprot.org/citations/10204397 | http://purl.uniprot.org/core/author | "Harrison L.G."xsd:string |
| http://purl.uniprot.org/citations/10204397 | http://purl.uniprot.org/core/author | "Holloway D.M."xsd:string |
| http://purl.uniprot.org/citations/10204397 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10204397 | http://purl.uniprot.org/core/name | "Math Biosci"xsd:string |
| http://purl.uniprot.org/citations/10204397 | http://purl.uniprot.org/core/pages | "271-290"xsd:string |
| http://purl.uniprot.org/citations/10204397 | http://purl.uniprot.org/core/title | "Suppression of positional errors in biological development."xsd:string |
| http://purl.uniprot.org/citations/10204397 | http://purl.uniprot.org/core/volume | "156"xsd:string |
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