http://purl.uniprot.org/citations/10213691 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10213691 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10213691 | http://www.w3.org/2000/01/rdf-schema#comment | "The von Hippel-Lindau (VHL) tumor suppressor gene is mutated in most human kidney cancers. The VHL protein is part of a complex that includes Elongin B, Elongin C, and Cullin-2, proteins associated with transcriptional elongation and ubiquitination. Here it is shown that the endogenous VHL complex in rat liver also includes Rbx1, an evolutionarily conserved protein that contains a RING-H2 fingerlike motif and that interacts with Cullins. The yeast homolog of Rbx1 is a subunit and potent activator of the Cdc53-containing SCFCdc4 ubiquitin ligase required for ubiquitination of the cyclin-dependent kinase inhibitor Sic1 and for the G1 to S cell cycle transition. These findings provide a further link between VHL and the cellular ubiquitination machinery."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.284.5414.657"xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.284.5414.657"xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Elledge S.J."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Elledge S.J."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Lane W.S."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Lane W.S."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Conaway J.W."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Conaway J.W."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Conaway R.C."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Conaway R.C."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Harper J.W."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Harper J.W."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Koepp D.M."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Koepp D.M."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Conrad M.N."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Conrad M.N."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Kamura T."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Kamura T."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Skowyra D."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Skowyra D."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Moreland R.J."xsd:string |
http://purl.uniprot.org/citations/10213691 | http://purl.uniprot.org/core/author | "Moreland R.J."xsd:string |