| http://purl.uniprot.org/citations/10230394 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10230394 | http://www.w3.org/2000/01/rdf-schema#comment | "Signaling pathways between cell surface receptors and the BCL-2 family of proteins regulate cell death. Survival factors induce the phosphorylation and inactivation of BAD, a proapoptotic member. Purification of BAD kinase(s) identified membrane-based cAMP-dependent protein kinase (PKA) as a BAD Ser-112 (S112) site-specific kinase. PKA-specific inhibitors blocked the IL-3-induced phosphorylation on S112 of endogenous BAD as well as mitochondria-based BAD S112 kinase activity. A blocking peptide that disrupts type II PKA holoenzyme association with A-kinase-anchoring proteins (AKAPs) also inhibited BAD phosphorylation and eliminated the BAD S112 kinase activity at mitochondria. Thus, the anchoring of PKA to mitochondria represents a focused subcellular kinase/substrate interaction that inactivates BAD at its target organelle in response to a survival factor."xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(00)80469-4"xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://purl.uniprot.org/core/author | "Mann M."xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://purl.uniprot.org/core/author | "Taylor S.S."xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://purl.uniprot.org/core/author | "Scott J.D."xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://purl.uniprot.org/core/author | "Wilm M."xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://purl.uniprot.org/core/author | "Harada H."xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://purl.uniprot.org/core/author | "Becknell B."xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://purl.uniprot.org/core/author | "Korsmeyer S.J."xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://purl.uniprot.org/core/author | "Huang L.J."xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10230394 | http://purl.uniprot.org/core/name | "Mol Cell"xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://purl.uniprot.org/core/pages | "413-422"xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://purl.uniprot.org/core/title | "Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A."xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://purl.uniprot.org/core/volume | "3"xsd:string |
| http://purl.uniprot.org/citations/10230394 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10230394 |
| http://purl.uniprot.org/citations/10230394 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10230394 |
| http://purl.uniprot.org/uniprot/#_Q61337-mappedCitation-10230394 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10230394 |
| http://purl.uniprot.org/uniprot/Q61337 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/10230394 |