| http://purl.uniprot.org/citations/10358032 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10358032 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10358032 | http://www.w3.org/2000/01/rdf-schema#comment | "RIP3 is a novel gene product containing a N-terminal kinase domain that shares extensive homology with the corresponding domain in RIP (receptor-interacting protein) and RIP2. Unlike RIP, which has a C-terminal death domain, and RIP2, which has a C-terminal caspase activation and recruitment domain, RIP3 has a unique C terminus. RIP3 binds RIP through its unique C-terminal segment and by virtue of this interaction is recruited to the tumor necrosis factor (TNF) receptor-1 signaling complex. Previous studies have shown that RIP mediates TNF-induced activation of the anti-apoptotic NF-kappaB pathway. RIP3, however, attenuates both RIP and TNF receptor-1-induced NF-kappaB activation. Overexpression studies revealed RIP3 to be a potent inducer of apoptosis, capable of selectively binding to large prodomain initiator caspases."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.274.24.16871"xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.274.24.16871"xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/author | "Baldwin D.T."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/author | "Baldwin D.T."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/author | "Lee J."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/author | "Lee J."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/author | "Sun X."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/author | "Sun X."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/author | "Dixit V.M."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/author | "Dixit V.M."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/author | "Stewart T.A."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/author | "Stewart T.A."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/author | "Navas T."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/author | "Navas T."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/pages | "16871-16875"xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/pages | "16871-16875"xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/title | "RIP3, a novel apoptosis-inducing kinase."xsd:string |
| http://purl.uniprot.org/citations/10358032 | http://purl.uniprot.org/core/title | "RIP3, a novel apoptosis-inducing kinase."xsd:string |