| http://purl.uniprot.org/citations/10364167 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10364167 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10364167 | http://www.w3.org/2000/01/rdf-schema#comment | "Mechanisms by which the human T-cell leukemia virus type I Tax oncoprotein activates NF-kappaB remain incompletely understood. Although others have described an interaction between Tax and a holo-IkappaB kinase (IKK) complex, the exact details of protein-protein contact are not fully defined. Here we show that Tax binds to neither IKK-alpha nor IKK-beta but instead complexes directly with IKK-gamma, a newly characterized component of the IKK complex. This direct interaction with IKK-gamma correlates with Tax-induced IkappaB-alpha phosphorylation and NF-kappaB activation. Thus, our findings establish IKK-gamma as a key molecule for adapting an oncoprotein-specific signaling to IKK-alpha and IKK-beta."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.274.25.17402"xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.274.25.17402"xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/author | "Jeang K.-T."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/author | "Jeang K.-T."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/author | "Jin D.-Y."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/author | "Jin D.-Y."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/author | "Nakano H."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/author | "Nakano H."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/author | "Kibler K.V."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/author | "Kibler K.V."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/author | "Giordano V."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/author | "Giordano V."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/pages | "17402-17405"xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/pages | "17402-17405"xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/title | "Role of adapter function in oncoprotein-mediated activation of NF-kappaB: human T-cell leukemia virus type I Tax interacts directly with IkappaB kinase gamma."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/title | "Role of adapter function in oncoprotein-mediated activation of NF-kappaB: human T-cell leukemia virus type I Tax interacts directly with IkappaB kinase gamma."xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/volume | "274"xsd:string |
| http://purl.uniprot.org/citations/10364167 | http://purl.uniprot.org/core/volume | "274"xsd:string |