| http://purl.uniprot.org/citations/10375498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10375498 | http://www.w3.org/2000/01/rdf-schema#comment | "Genetic studies have identified an unusual transvection process in the Abdominal-B (Abd-B) locus of Drosophila. In some cases distal infraabdominal (iab) regulatory domains continue to activate the Abd-B promoter even when translocated onto different chromosomes. Transvection depends on an approx. 10 kb genomic DNA sequence, termed the transvection mediating region (tmr), located immediately downstream of the Abd-B transcription unit. Here we report a detailed analysis of this region. Different DNA fragments from the tmr were inserted into a variety of P-transformation vectors. Analyses of reporter gene expression in transgenic embryos and adults identify at least three cis-regulatory elements, including two enhancers (IAB7 and IAB8) and a new insulator DNA (Frontabdominal-8, Fab-8). Evidence is also presented for a Polycomb Response Element (PRE) linked to the IAB8 enhancer, and an internal promoter in the iab-8 domain, which transcribes the iab-7 and iab-8 cis-regulatory DNA, including the Fab-8 insulator. We discuss the significance of these findings with regard to Abd-B transvection and long-range enhancer-promoter interactions in mammalian globin loci."xsd:string |
| http://purl.uniprot.org/citations/10375498 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.126.14.3057"xsd:string |
| http://purl.uniprot.org/citations/10375498 | http://purl.uniprot.org/core/author | "Zhou J."xsd:string |
| http://purl.uniprot.org/citations/10375498 | http://purl.uniprot.org/core/author | "Levine M."xsd:string |
| http://purl.uniprot.org/citations/10375498 | http://purl.uniprot.org/core/author | "Burks C."xsd:string |
| http://purl.uniprot.org/citations/10375498 | http://purl.uniprot.org/core/author | "Ashe H."xsd:string |
| http://purl.uniprot.org/citations/10375498 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10375498 | http://purl.uniprot.org/core/name | "Development"xsd:string |
| http://purl.uniprot.org/citations/10375498 | http://purl.uniprot.org/core/pages | "3057-3065"xsd:string |
| http://purl.uniprot.org/citations/10375498 | http://purl.uniprot.org/core/title | "Characterization of the transvection mediating region of the abdominal-B locus in Drosophila."xsd:string |
| http://purl.uniprot.org/citations/10375498 | http://purl.uniprot.org/core/volume | "126"xsd:string |
| http://purl.uniprot.org/citations/10375498 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10375498 |
| http://purl.uniprot.org/citations/10375498 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10375498 |
| http://purl.uniprot.org/uniprot/#_P14003-mappedCitation-10375498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10375498 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KGT1-mappedCitation-10375498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10375498 |
| http://purl.uniprot.org/uniprot/#_A0A0B4LGC1-mappedCitation-10375498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10375498 |
| http://purl.uniprot.org/uniprot/#_A0A126GUV3-mappedCitation-10375498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10375498 |
| http://purl.uniprot.org/uniprot/#_A0A126GUV9-mappedCitation-10375498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10375498 |
| http://purl.uniprot.org/uniprot/#_A4V304-mappedCitation-10375498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10375498 |
| http://purl.uniprot.org/uniprot/#_P09087-mappedCitation-10375498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10375498 |
| http://purl.uniprot.org/uniprot/#_P09957-mappedCitation-10375498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10375498 |
| http://purl.uniprot.org/uniprot/#_P10090-mappedCitation-10375498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10375498 |
| http://purl.uniprot.org/uniprot/#_P10627-mappedCitation-10375498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10375498 |
| http://purl.uniprot.org/uniprot/#_Q86P38-mappedCitation-10375498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10375498 |