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http://purl.uniprot.org/citations/10381339http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10381339http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10381339http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Citation
http://purl.uniprot.org/citations/10381339http://www.w3.org/2000/01/rdf-schema#comment"Here we report the preliminary characterization of Yor180Cp, a novel peroxisomal protein involved in fatty acid metabolism in the yeast Saccharomyces cerevisiae. A computer-based screen identified Yor180Cp as a putative peroxisomal protein, and Yor180Cp targeted GFP to peroxisomes in a PEX8-dependent manner. Yor180Cp was also detected by mass spectrometric analysis of an HPLC-separated extract of yeast peroxisomal matrix proteins. YOR180C is upregulated during growth on oleic acid, and deletion of YOR180C from the yeast genome resulted in a mild but significant growth defect on oleic acid, indicating a role for Yor180Cp in fatty acid metabolism. In addition, we observed that yor180cDelta cells fail to efficiently import the enzyme Delta3,Delta2-enoyl-CoA isomerase (Eci1p) to peroxisomes. This result suggested that Yor180Cp might associate with Eci1p in vivo, and a Yor180Cp-Eci1p interaction was detected using the yeast two-hybrid system. Potential roles for Yor180Cp in peroxisomal fatty acid metabolism are discussed."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.1999.0860"xsd:string
http://purl.uniprot.org/citations/10381339http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.1999.0860"xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Schulz K."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Schulz K."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Schulz H."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Schulz H."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Geraghty M.T."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Geraghty M.T."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Geisbrecht B.V."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Geisbrecht B.V."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Gould S.J."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Gould S.J."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Erdmann R."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Erdmann R."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Nau K."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/author"Nau K."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/10381339http://purl.uniprot.org/core/pages"28-34"xsd:string