http://purl.uniprot.org/citations/10381349 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10381349 | http://www.w3.org/2000/01/rdf-schema#comment | "O- and N-glycans included in erythrocyte membrane glycoproteins from beta1,4-galactosyltransferase I (GalT-I) knockout mice were analyzed to examine how this enzyme deficiency affects glycosylation of proteins in erythroid cells. The results indicated that greater than 80% of core 2 O-glycans from GalT-I-/-mice are not galactosylated by beta1,4 linkage, resulting in the expression of Neu5Acalpha2 --> 3Galbeta1 --> 3(GlcNAcbeta1 --> 6)GalNAc, while core 2 O-glycans from GalT-I+/+ mice are fully galactosylated and occur as Neu5Acalpha2 --> 3Galbeta1 --> 3(Neu5Acalpha2 --> 3Galbeta1 --> 4GlcNAcbeta1 --> 6)GalNAc. On the other hand, beta1, 4-galactosylation of N-glycans of the mutant was approximately 60% that of the wild type. Thus, it is suggested that GalT-I is predominantly responsible for beta1,4-galactosylation of the core 2 O-glycan branch in erythroid cells."xsd:string |
http://purl.uniprot.org/citations/10381349 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1999.0872"xsd:string |
http://purl.uniprot.org/citations/10381349 | http://purl.uniprot.org/core/author | "Asano M."xsd:string |
http://purl.uniprot.org/citations/10381349 | http://purl.uniprot.org/core/author | "Iwakura Y."xsd:string |
http://purl.uniprot.org/citations/10381349 | http://purl.uniprot.org/core/author | "Kotani N."xsd:string |
http://purl.uniprot.org/citations/10381349 | http://purl.uniprot.org/core/author | "Takasaki S."xsd:string |
http://purl.uniprot.org/citations/10381349 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10381349 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
http://purl.uniprot.org/citations/10381349 | http://purl.uniprot.org/core/pages | "94-98"xsd:string |
http://purl.uniprot.org/citations/10381349 | http://purl.uniprot.org/core/title | "Impaired galactosylation of core 2 O-glycans in erythrocytes of beta1,4-galactosyltransferase knockout mice."xsd:string |
http://purl.uniprot.org/citations/10381349 | http://purl.uniprot.org/core/volume | "260"xsd:string |
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