| http://purl.uniprot.org/citations/10383417 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10383417 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10383417 | http://www.w3.org/2000/01/rdf-schema#comment | "STAM containing an SH3 (Src homology 3) domain and an immunoreceptor tyrosine-based activation motif was previously revealed to be implicated in signaling pathways immediately downstream of Jak2 and Jak3 tyrosine kinases associated with cytokine receptors. We molecularly cloned a novel molecule interacting with the SH3 domain of STAM, which was named AMSH (associated molecule with the SH3 domain of STAM). AMSH contains a putative bipartite nuclear localization signal and a homologous region of a c-Jun activation domain-binding protein 1 (JAB1) subdomain in addition to a binding site for the SH3 domain of STAM. AMSH mutant deleted of the C-terminal half conferred dominant negative effects on signaling for DNA synthesis and c-myc induction mediated by interleukin 2 and granulocyte macrophage-colony-stimulating factor. These results suggest that AMSH plays a critical role in the cytokine-mediated intracellular signal transduction downstream of the Jak2/Jak3.STAM complex."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.274.27.19129"xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.274.27.19129"xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Endo Y."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Endo Y."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Kasai H."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Kasai H."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Fujita T."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Fujita T."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Tanaka N."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Tanaka N."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Kaneko K."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Kaneko K."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Asao H."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Asao H."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Sugamura K."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Sugamura K."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Takeshita T."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/author | "Takeshita T."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/10383417 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |