| http://purl.uniprot.org/citations/10384981 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10384981 | http://www.w3.org/2000/01/rdf-schema#comment | "Retrograde transport of proteins from the Golgi to the endoplasmic reticulum (ER) has been the subject of some interest in the recent past. Here a new thermosensitive yeast mutant defective in retrieval of dilysine-tagged proteins from the Golgi back to the endoplasmic reticulum was characterized. The ret4-1 mutant also exhibited a selective defect in forward ER-to-Golgi transport of some secreted proteins at the non-permissive temperature. The corresponding RET4 gene was found to encode Glo3p, a GTPase-activating protein (GAP) specific for ADP-ribosylation factor (ARF). In vitro, the Glo3 thermosensitive mutant showed a reduced ARF1-GAP activity. The Glo3 protein belongs to a family of zinc finger proteins that may include additional ARF-GAPs. Gene deletion experiments of other family members showed that only GLO3 deletion resulted in impaired retrieval of dilysine-tagged proteins back to the ER. These results demonstrate that Glo3p is the main ARF-GAP specifically involved in ER retrieval."xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0171-9335(99)80064-8"xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://purl.uniprot.org/core/author | "Cosson P."xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://purl.uniprot.org/core/author | "Lefkir Y."xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://purl.uniprot.org/core/author | "Letourneur F."xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://purl.uniprot.org/core/author | "de Chassey B."xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://purl.uniprot.org/core/author | "Hennecke S."xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://purl.uniprot.org/core/author | "Cassel D."xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://purl.uniprot.org/core/author | "Pick E."xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://purl.uniprot.org/core/author | "Dogic D."xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10384981 | http://purl.uniprot.org/core/name | "Eur J Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://purl.uniprot.org/core/pages | "305-310"xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://purl.uniprot.org/core/title | "The ADP-ribosylation factor GTPase-activating protein Glo3p is involved in ER retrieval."xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://purl.uniprot.org/core/volume | "78"xsd:string |
| http://purl.uniprot.org/citations/10384981 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10384981 |
| http://purl.uniprot.org/citations/10384981 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10384981 |
| http://purl.uniprot.org/uniprot/#_P38682-mappedCitation-10384981 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10384981 |
| http://purl.uniprot.org/uniprot/P38682 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/10384981 |