| http://purl.uniprot.org/citations/10388805 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10388805 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10388805 | http://www.w3.org/2000/01/rdf-schema#comment | "We have isolated a mutation in nup184(nup184-1) that is synthetically lethal with the mRNA export defective rae1-167 mutation in Schizosaccharomyces pombe. The consequence of the synthetic lethality is a defect in mRNA export. The predicted Nup184p is similar to Nup188p of Saccharomyces cerevisiae, and a Nup184p-GFP fusion localizes to the nuclear periphery in a punctate pattern. The Deltanup184 null mutant is viable and also is synthetically lethal with rae1-167. In a rae1(+) background, both the nup184-1 and Deltanup184 mutations confer sensitivity to growth in nutrient-rich medium (YES) that is accompanied by nuclear poly(A)+ RNA accumulation. Removal of the cAMP-dependent protein kinase, Pka1p, relieved the growth and mRNA export defects of nup184 mutants when grown in nutrient-rich medium. The activation of Pka1p is necessary, but not sufficient, to cause the severe poly(A)+ RNA export defects when nup184 mutant cells are incubated in YES, suggesting nutritional status can also regulate poly(A)+ RNA export. Our results suggest that the regulation of poly(A)+ RNA export by Pka1p kinase appears to be indirect, via a translation-dependent step, but post-translationally in response to YES."xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/152.3.827"xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/152.3.827"xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/author | "Dhar R."xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/author | "Dhar R."xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/author | "Yoon J.H."xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/author | "Yoon J.H."xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/author | "Whalen W.A."xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/author | "Whalen W.A."xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/author | "Shen R."xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/author | "Shen R."xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/pages | "827-838"xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/pages | "827-838"xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/title | "Regulation of mRNA export by nutritional status in fission yeast."xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/title | "Regulation of mRNA export by nutritional status in fission yeast."xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/volume | "152"xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://purl.uniprot.org/core/volume | "152"xsd:string |
| http://purl.uniprot.org/citations/10388805 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10388805 |
| http://purl.uniprot.org/citations/10388805 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10388805 |