| http://purl.uniprot.org/citations/10394362 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10394362 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10394362 | http://www.w3.org/2000/01/rdf-schema#comment | "Activation of ERK/MAPK is a key event downstream of RAS. The duration, extent, and timing of MAPK activity is integral to signal specificity. Consequently, inactivation of MAPK by phosphatases has emerged as a critical element in the precise control of signal output. We have cloned and characterized a novel cytoplasmic protein tyrosine phosphatase, PTP-ER, which is related to mammalian PCPTP1, LC-PTP/HePTP, and STEP tyrosine phosphatases. PTP-ER mutants produce extra R7 cells and enhance activated Ras1 signaling. Ectopic expression of PTP-ER dramatically inhibits RAS1/MAPK signaling. PTP-ER binds to and inactivates Drosophila ERK/MAPK; however, it is unable to dephosphorylate and downregulate Drosophila MAPKSevenmaker. Resistance to PTP-ER activity partially accounts for the Sevenmaker mutant phenotype."xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.org/dc/terms/identifier | "doi:10.1016/S1097-2765(01)80006-X"xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(01)80006-x"xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/author | "Rubin G.M."xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/author | "Rubin G.M."xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/author | "Karim F.D."xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/author | "Karim F.D."xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/name | "Mol Cell"xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/pages | "741-750"xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/pages | "741-750"xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/title | "PTP-ER, a novel tyrosine phosphatase, functions downstream of Ras1 to downregulate MAP kinase during Drosophila eye development."xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/title | "PTP-ER, a novel tyrosine phosphatase, functions downstream of Ras1 to downregulate MAP kinase during Drosophila eye development."xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/volume | "3"xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://purl.uniprot.org/core/volume | "3"xsd:string |
| http://purl.uniprot.org/citations/10394362 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10394362 |
| http://purl.uniprot.org/citations/10394362 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10394362 |
| http://purl.uniprot.org/citations/10394362 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10394362 |
| http://purl.uniprot.org/citations/10394362 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10394362 |
| http://purl.uniprot.org/uniprot/Q9W2F3 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/10394362 |
| http://purl.uniprot.org/uniprot/P40417#attribution-0D9416AFE828C4AD47508DB6F47A308F | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10394362 |