| http://purl.uniprot.org/citations/10395907 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10395907 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10395907 | http://www.w3.org/2000/01/rdf-schema#comment | "A new type of peroxiredoxin, named 1-Cys peroxiredoxin (1-Cys Prx), reduces hydrogen peroxide with the use of electrons from unidentified electron donor(s). We have isolated the mouse gene encoding 1-Cys Prx (CP-3) and shown that it is comprised of five exons and four introns. Analysis of 5' flanking regions revealed binding sequences of several putative transcription factors such as Sp1, Pit-1a, c-Jun, c-Myc and YY1. It is noticeable that several potential Sp1 binding sites assigned the -60 through -96bp from putative transcription initiation site. The gel shift assays showed that Sp1 and Pit-1a bind specifically to each binding site in 1-Cys Prx promoter. We also isolated two highly related genes such as CP-2 and CP-5. These genes are encoded by single exons, and show 85% of nucleotide sequence homology with the CP-3. The structural features of these genes suggest that they might be intronless genes derived from the CP-3 by the mechanism involving retrotransposition. In addition, our data suggest that they are inserted to a specific site of the mouse L1 repetitive element. The 1-Cys Prx was actively transcribed in a variety of adult tissues as well as in the developing embryos. These results suggest that only the 1-Cys Prx gene might be relevant for studying the function of the 1-Cys Prx in the murine system."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0378-1119(99)00190-0"xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0378-1119(99)00190-0"xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Yu D.-Y."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Yu D.-Y."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Yu S.-L."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Yu S.-L."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Rhee S.G."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Rhee S.G."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Lee T.-H."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Lee T.-H."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Kim S.-U."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Kim S.-U."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Kang S.W."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Kang S.W."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Choi I."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Choi I."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Kim Y.-M."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/author | "Kim Y.-M."xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
| http://purl.uniprot.org/citations/10395907 | http://purl.uniprot.org/core/name | "Gene"xsd:string |