| http://purl.uniprot.org/citations/10398605 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10398605 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10398605 | http://www.w3.org/2000/01/rdf-schema#comment | "Xeroderma pigmentosum (XP) is an autosomal recessive disease characterized by a high incidence of skin cancers. Yeast RAD30 encodes a DNA polymerase involved in the error-free bypass of ultraviolet (UV) damage. Here it is shown that XP variant (XP-V) cell lines harbor nonsense or frameshift mutations in hRAD30, the human counterpart of yeast RAD30. Of the eight mutations identified, seven would result in a severely truncated hRad30 protein. These results indicate that defects in hRAD30 cause XP-V, and they suggest that error-free replication of UV lesions by hRad30 plays an important role in minimizing the incidence of sunlight-induced skin cancers."xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.285.5425.263"xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.285.5425.263"xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/author | "Johnson R.E."xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/author | "Johnson R.E."xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/author | "Prakash L."xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/author | "Prakash L."xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/author | "Prakash S."xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/author | "Prakash S."xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/author | "Kondratick C.M."xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/author | "Kondratick C.M."xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/pages | "263-265"xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/pages | "263-265"xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/title | "hRAD30 mutations in the variant form of xeroderma pigmentosum."xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/title | "hRAD30 mutations in the variant form of xeroderma pigmentosum."xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/volume | "285"xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://purl.uniprot.org/core/volume | "285"xsd:string |
| http://purl.uniprot.org/citations/10398605 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10398605 |
| http://purl.uniprot.org/citations/10398605 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10398605 |