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http://purl.uniprot.org/citations/10403379http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10403379http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10403379http://www.w3.org/2000/01/rdf-schema#comment"N-copine is a novel two C2 domain protein that shows Ca2(+)-dependent phospholipid binding and membrane association. By using yeast two-hybrid assays, we identified OS-9 as a protein capable of interacting with N-copine. We further revealed that the second C2 domain of N-copine bound with the carboxy-terminal region of OS-9. Their interaction in vivo was also confirmed by co-immunoprecipitation from 293E cells co-expressing transfected N-copine and OS-9. In vitro binding assays showed that this interaction was Ca2(+)-dependent. By Northern blot analysis, N-copine and OS-9 were co-expressed in the same regions of human brain. These results reveal that OS-9 is a potential target of N-copine."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(99)00700-0"xsd:string
http://purl.uniprot.org/citations/10403379http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(99)00700-0"xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/author"Nakayama T."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/author"Nakayama T."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/author"Yaoi T."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/author"Yaoi T."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/author"Yoshie O."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/author"Yoshie O."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/author"Sakata T."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/author"Sakata T."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/author"Kuwajima G."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/author"Kuwajima G."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/pages"77-80"xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/pages"77-80"xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/title"Ca2(+)-dependent interaction of N-copine, a member of the two C2 domain protein family, with OS-9, the product of a gene frequently amplified in osteosarcoma."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/title"Ca2(+)-dependent interaction of N-copine, a member of the two C2 domain protein family, with OS-9, the product of a gene frequently amplified in osteosarcoma."xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/volume"453"xsd:string
http://purl.uniprot.org/citations/10403379http://purl.uniprot.org/core/volume"453"xsd:string