http://purl.uniprot.org/citations/10404228 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10404228 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10404228 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
http://purl.uniprot.org/citations/10404228 | http://www.w3.org/2000/01/rdf-schema#comment | "Almost half of the entire set of predicted genomic products from Methanococcus jannaschii are classified as functionally unknown hypothetical proteins. We present a structure-based identification of the biochemical function of a protein with an as yet unknown function from a M. jannaschii gene, Mj0226. The crystal structure of Mj0226 protein determined at 2.2 A resolution reveals that the protein is a homodimer and each monomer folds into an elongated alpha/beta structure of a new fold family. Comparisons of Mj0226 protein with protein structures in the database, however, indicate that one part of the protein is homologous to some of the nucleotide-binding proteins. Biochemical analysis shows that Mj0226 protein is a novel nucleotide triphosphatase that can efficiently hydrolyze nonstandard nucleotides such as XTP to XMP or ITP to IMP, but not the standard nucleotides, in the presence of Mg2+ or Mn2+ ions."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.org/dc/terms/identifier | "doi:10.1038/10745"xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.org/dc/terms/identifier | "doi:10.1038/10745"xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/author | "Hwang K.Y."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/author | "Hwang K.Y."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/author | "Cho Y."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/author | "Cho Y."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/author | "Kim S.-H."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/author | "Kim S.-H."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/author | "Han Y.S."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/author | "Han Y.S."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/author | "Chung J.H."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/author | "Chung J.H."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/name | "Nat. Struct. Biol."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/name | "Nat. Struct. Biol."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/pages | "691-696"xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/pages | "691-696"xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/title | "Structure-based identification of a novel NTPase from Methanococcus jannaschii."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/title | "Structure-based identification of a novel NTPase from Methanococcus jannaschii."xsd:string |
http://purl.uniprot.org/citations/10404228 | http://purl.uniprot.org/core/volume | "6"xsd:string |