| http://purl.uniprot.org/citations/10410902 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10410902 | http://www.w3.org/2000/01/rdf-schema#comment | "Galectin-7 is a 14 KDa member of the galectin family that we have cloned from human, rat and mouse. Our previous studies have shown that in the adult, galectin-7 is expressed in all cell layers of epidermis and of other stratified epithelia such asthe cornea and the lining of the oesophagus. This suggested that galectin-7 expression might be induced at a particular stage in the embryonic development of stratified epithelia. In the present study we have investigated this hypothesis by in situ hybridization of galectin-7 mRNA in mouse embryos. Starting from E13.5, weak expression of galectin-7 was detected in bilayered ectoderm, and stronger expression was found in areas of embryonic epidermis where stratification was more advanced. Galectin-7 expression was maintained in all living layers after epidermal development was completed. Galectin-7 was also strongly and specifically expressed in stratified regions of ectodermally-derived non-epidermal epithelia such as the lining of the buccal cavity, the oesophagus and the ano-rectal region. In contrast, no expression of galectin-7 was found in epithelia derived from endoderm, such as lining of the intestine, kidney and lung. Our results demonstrate that galectin-7 is expressed in all stratified epithelia examined so far, and that the onset of its expression coincides with the first visible signs of stratification. These results establish galectin-7 as the first region-independent marker of epithelial stratification."xsd:string |
| http://purl.uniprot.org/citations/10410902 | http://purl.uniprot.org/core/author | "Magnaldo T."xsd:string |
| http://purl.uniprot.org/citations/10410902 | http://purl.uniprot.org/core/author | "Timmons P.M."xsd:string |
| http://purl.uniprot.org/citations/10410902 | http://purl.uniprot.org/core/author | "Colnot C."xsd:string |
| http://purl.uniprot.org/citations/10410902 | http://purl.uniprot.org/core/author | "Poirier F."xsd:string |
| http://purl.uniprot.org/citations/10410902 | http://purl.uniprot.org/core/author | "Cail I."xsd:string |
| http://purl.uniprot.org/citations/10410902 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10410902 | http://purl.uniprot.org/core/name | "Int J Dev Biol"xsd:string |
| http://purl.uniprot.org/citations/10410902 | http://purl.uniprot.org/core/pages | "229-235"xsd:string |
| http://purl.uniprot.org/citations/10410902 | http://purl.uniprot.org/core/title | "Expression of galectin-7 during epithelial development coincides with the onset of stratification."xsd:string |
| http://purl.uniprot.org/citations/10410902 | http://purl.uniprot.org/core/volume | "43"xsd:string |
| http://purl.uniprot.org/citations/10410902 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10410902 |
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