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http://purl.uniprot.org/citations/10413050http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10413050http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10413050http://www.w3.org/2000/01/rdf-schema#comment"One of the candidate schistosome antigens for the development of a circulating antigen detection diagnostic assay is the circulating cathodic antigen (CCA). Detection of CCA in urine provides a non-invasive assay with high sensitivity. Previously we reported that CCA is secreted in patients' urine as a small molecular weight material which is probably of a proteinaceous nature. In an attempt to further characterize the secreted component of CCA, we used a monoclonal antibody (MAb) reactive with urine-CCA to isolate an adult worm cDNA clone (SmN3-1) that encodes the polypeptide backbone of CCA. The sequence, gene organization and expression of SmN3-1 were analyzed. The 1.6 kb nucleotide and 347 amino acid sequences of SmN3-1 showed no significant homology to any published sequence. The size and antigenic properties of the expression product of SmN3-1 in Escherichia coli greatly resembled the CCA molecule excreted in urine, suggesting that the latter is primarily composed of the protein element of CCA."xsd:string
http://purl.uniprot.org/citations/10413050http://purl.org/dc/terms/identifier"doi:10.1016/s0166-6851(99)00068-7"xsd:string
http://purl.uniprot.org/citations/10413050http://purl.org/dc/terms/identifier"doi:10.1016/s0166-6851(99)00068-7"xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/author"Harrison R.A."xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/author"Harrison R.A."xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/author"Abdeen H.H."xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/author"Abdeen H.H."xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/author"Attallah A.F."xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/author"Attallah A.F."xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/author"Mansour M.M."xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/author"Mansour M.M."xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/name"Mol. Biochem. Parasitol."xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/name"Mol. Biochem. Parasitol."xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/pages"149-159"xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/pages"149-159"xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/title"Molecular cloning and characterization of the polypeptide backbone of Schistosoma mansoni circulating cathodic antigen."xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/title"Molecular cloning and characterization of the polypeptide backbone of Schistosoma mansoni circulating cathodic antigen."xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/volume"101"xsd:string
http://purl.uniprot.org/citations/10413050http://purl.uniprot.org/core/volume"101"xsd:string
http://purl.uniprot.org/citations/10413050http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10413050
http://purl.uniprot.org/citations/10413050http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10413050