| http://purl.uniprot.org/citations/10413469 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10413469 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10413469 | http://www.w3.org/2000/01/rdf-schema#comment | "Previously we showed that the yeast proteins Spt16 (Cdc68) and Pob3 are physically associated, and interact physically and genetically with the catalytic subunit of DNA polymerase alpha, Pol1 [Wittmeyer and Formosa (1997) Mol. Cell. Biol. 17, 4178-4190]. Here we show that purified Spt16 and Pob3 form a stable, abundant, elongated heterodimer and provide evidence that this is the functional form of these proteins. Genetic interactions between mutations in SPT16 and POB3 support the importance of the Spt16-Pob3 interaction in vivo. Spt16, Pob3, and Pol1 proteins were all found to localize to the nucleus in S. cerevisiae. A portion of the total cellular Spt16-Pob3 was found to be chromatin-associated, consistent with the proposed roles in modulating chromatin function. Some of the Spt16-Pob3 complex was found to copurify with the yeast DNA polymerase alpha/primase complex, further supporting a connection between Spt16-Pob3 and DNA replication."xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.org/dc/terms/identifier | "doi:10.1021/bi982851d"xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.org/dc/terms/identifier | "doi:10.1021/bi982851d"xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/author | "Joss L."xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/author | "Joss L."xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/author | "Wittmeyer J."xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/author | "Wittmeyer J."xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/author | "Formosa T."xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/author | "Formosa T."xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/pages | "8961-8971"xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/pages | "8961-8971"xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/title | "Spt16 and Pob3 of Saccharomyces cerevisiae form an essential, abundant heterodimer that is nuclear, chromatin-associated, and copurifies with DNA polymerase alpha."xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/title | "Spt16 and Pob3 of Saccharomyces cerevisiae form an essential, abundant heterodimer that is nuclear, chromatin-associated, and copurifies with DNA polymerase alpha."xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/volume | "38"xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://purl.uniprot.org/core/volume | "38"xsd:string |
| http://purl.uniprot.org/citations/10413469 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10413469 |
| http://purl.uniprot.org/citations/10413469 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10413469 |
| http://purl.uniprot.org/citations/10413469 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10413469 |
| http://purl.uniprot.org/citations/10413469 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10413469 |