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http://purl.uniprot.org/citations/10426994http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10426994http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10426994http://www.w3.org/2000/01/rdf-schema#comment"Many immune receptors are composed of separate ligand-binding and signal-transducing subunits. In natural killer (NK) and T cells, DAP10 was identified as a cell surface adaptor protein in an activating receptor complex with NKG2D, a receptor for the stress-inducible and tumor-associated major histocompatibility complex molecule MICA. Within the DAP10 cytoplasmic domain, an Src homology 2 (SH2) domain-binding site was capable of recruiting the p85 subunit of the phosphatidylinositol 3-kinase (PI 3-kinase), providing for NKG2D-dependent signal transduction. Thus, NKG2D-DAP10 receptor complexes may activate NK and T cell responses against MICA-bearing tumors."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.org/dc/terms/identifier"doi:10.1126/science.285.5428.730"xsd:string
http://purl.uniprot.org/citations/10426994http://purl.org/dc/terms/identifier"doi:10.1126/science.285.5428.730"xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Song Y."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Song Y."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Wu J."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Wu J."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Bauer S."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Bauer S."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Lanier L.L."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Lanier L.L."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Spies T."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Spies T."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Phillips J.H."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Phillips J.H."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Bakker A.B.H."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/author"Bakker A.B.H."xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/pages"730-732"xsd:string
http://purl.uniprot.org/citations/10426994http://purl.uniprot.org/core/pages"730-732"xsd:string