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http://purl.uniprot.org/citations/10428035http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10428035http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10428035http://www.w3.org/2000/01/rdf-schema#comment"Xenopus 13S condensin converts interphase chromatin into mitotic-like chromosomes, and, in the presence of ATP and a type I topoisomerase, introduces (+) supercoils into DNA. The specific production of (+) trefoil knots in the presence of condensin and a type II topoisomerase shows that condensin reconfigures DNA by introducing an ordered, global, (+) writhe. Knotting required ATP hydrolysis and cell cycle-specific phosphorylation of condensin. Condensin bound preferentially to (+) supercoiled DNA in the presence of ATP but not in its absence. Our results suggest a mechanism for the compaction of chromatin by condensin during mitosis."xsd:string
http://purl.uniprot.org/citations/10428035http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(00)81018-1"xsd:string
http://purl.uniprot.org/citations/10428035http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(00)81018-1"xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/author"Kimura K."xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/author"Kimura K."xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/author"Hirano T."xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/author"Hirano T."xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/author"Cozzarelli N.R."xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/author"Cozzarelli N.R."xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/author"Rybenkov V.V."xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/author"Rybenkov V.V."xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/author"Crisona N.J."xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/author"Crisona N.J."xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/pages"239-248"xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/pages"239-248"xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/title"13S condensin actively reconfigures DNA by introducing global positive writhe: implications for chromosome condensation."xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/title"13S condensin actively reconfigures DNA by introducing global positive writhe: implications for chromosome condensation."xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/volume"98"xsd:string
http://purl.uniprot.org/citations/10428035http://purl.uniprot.org/core/volume"98"xsd:string