| http://purl.uniprot.org/citations/10433268 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10433268 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10433268 | http://www.w3.org/2000/01/rdf-schema#comment | "NMDA receptors are linked to intracellular cytoskeletal and signaling molecules via the PSD-95 protein complex. We report a novel family of postsynaptic density (PSD) proteins, termed Shank, that binds via its PDZ domain to the C terminus of PSD-95-associated protein GKAP. A ternary complex of Shank/GKAP/PSD-95 assembles in heterologous cells and can be coimmunoprecipitated from rat brain. Synaptic localization of Shank in neurons is inhibited by a GKAP splice variant that lacks the Shank-binding C terminus. In addition to its PDZ domain, Shank contains a proline-rich region that binds to cortactin and a SAM domain that mediates multimerization. Shank may function as a scaffold protein in the PSD, potentially cross-linking NMDA receptor/PSD-95 complexes and coupling them to regulators of the actin cytoskeleton."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(00)80809-0"xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(00)80809-0"xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Kim E."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Kim E."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Xiao B."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Xiao B."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Sala C."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Sala C."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Sheng M."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Sheng M."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Worley P.F."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Worley P.F."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Weinberg R.J."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Weinberg R.J."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Naisbitt S."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Naisbitt S."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Tu J.C."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Tu J.C."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Valtschanoff J."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/author | "Valtschanoff J."xsd:string |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10433268 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |