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http://purl.uniprot.org/citations/10438879http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10438879http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10438879http://www.w3.org/2000/01/rdf-schema#comment"We demonstrated that infection of 17Cl-1 cells with the murine coronavirus mouse hepatitis virus (MHV) induced caspase-dependent apoptosis. MHV-infected DBT cells did not show apoptotic changes, indicating that apoptosis was not a universal mechanism of cell death in MHV-infected cells. Expression of MHV structural proteins by recombinant vaccinia viruses showed that expression of MHV E protein induced apoptosis in DBT cells, whereas expression of other MHV structural proteins, including S protein, M protein, N protein, and hemagglutinin-esterase protein, failed to induce apoptosis. MHV E protein-mediated apoptosis was suppressed by a high level of Bcl-2 oncogene expression. Our data showed that MHV E protein is a multifunctional protein; in addition to its known function in coronavirus envelope formation, it also induces apoptosis."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.org/dc/terms/identifier"doi:10.1128/jvi.73.9.7853-7859.1999"xsd:string
http://purl.uniprot.org/citations/10438879http://purl.org/dc/terms/identifier"doi:10.1128/jvi.73.9.7853-7859.1999"xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/author"Makino S."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/author"Makino S."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/author"Chen C.-J."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/author"Chen C.-J."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/author"Yu X."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/author"Yu X."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/author"An S."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/author"An S."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/author"Leibowitz J.L."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/author"Leibowitz J.L."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/name"J. Virol."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/name"J. Virol."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/pages"7853-7859"xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/pages"7853-7859"xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/title"Induction of apoptosis in murine coronavirus-infected cultured cells and demonstration of E protein as an apoptosis inducer."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/title"Induction of apoptosis in murine coronavirus-infected cultured cells and demonstration of E protein as an apoptosis inducer."xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/volume"73"xsd:string
http://purl.uniprot.org/citations/10438879http://purl.uniprot.org/core/volume"73"xsd:string