http://purl.uniprot.org/citations/10441496 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10441496 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10441496 | http://www.w3.org/2000/01/rdf-schema#comment | "Apaf-1, the human C. elegans Ced-4 homologue, plays a crucial role in mitochondrial mediated apoptosis. To determine whether a mutant Apaf-1 is involved in the pathogenesis of malignant lymphomas, we performed sequence analysis of its transcriptional gene product. Therefore, cDNAs coding for Apaf-1 were examined in six lymphoma derived cell lines, in three non-lymphoid tumor cell lines, as well as in peripheral blood lymphocytes and in tissue from heart, kidney, and liver by RT-PCR. These studies did not disclose the expected tumor related alterations but led instead to the identification of three novel forms of Apaf-1. These forms vary in length, but contain all functional domains formerly characterized in the Apaf-1 protein. The results indicate that the previously published sequence is not the Apaf-1 form most widely expressed."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1999.1124"xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1999.1124"xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/author | "Stein H."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/author | "Stein H."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/author | "Duerkop H."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/author | "Duerkop H."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/author | "Hahn C."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/author | "Hahn C."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/author | "Hirsch B."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/author | "Hirsch B."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/author | "Jahnke D."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/author | "Jahnke D."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/pages | "746-749"xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/pages | "746-749"xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/title | "Three new types of Apaf-1 in mammalian cells."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/title | "Three new types of Apaf-1 in mammalian cells."xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/volume | "261"xsd:string |
http://purl.uniprot.org/citations/10441496 | http://purl.uniprot.org/core/volume | "261"xsd:string |