RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/10445029http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10445029http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10445029http://www.w3.org/2000/01/rdf-schema#comment"Genetic and biochemical studies indicate that the evolutionarily conserved Swi/Snf complex acts at a subset of genes to help transcriptional activators function on chromatin templates. The mechanism by which this complex is targeted to specific chromosomal loci remains unknown. We show that Swi/Snf is required for expression of the yeast histone HTA1-HTB1 locus because of the role of Hir1p and Hir2p corepressors in negatively regulating transcription. Snf5p, Snf2p/Swi2p, and Swi3p, three components of the yeast Swi/Snf complex, coimmunoprecipitate with each Hir protein, and Snf5p is maximally associated with the HTA1-HTB1 promoter when the Hir-based repression system is intact and the Swi/Snf complex is functional. The data support a role for the Hir repressors in the gene-specific targeting of Swi/Snf."xsd:string
http://purl.uniprot.org/citations/10445029http://purl.org/dc/terms/identifier"doi:10.1016/s1097-2765(00)80189-6"xsd:string
http://purl.uniprot.org/citations/10445029http://purl.org/dc/terms/identifier"doi:10.1016/s1097-2765(00)80189-6"xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/author"Dimova D."xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/author"Dimova D."xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/author"Osley M.A."xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/author"Osley M.A."xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/author"Eguchi S."xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/author"Eguchi S."xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/author"Furgeson S."xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/author"Furgeson S."xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/author"Nackerdien Z."xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/author"Nackerdien Z."xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/name"Mol. Cell"xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/name"Mol. Cell"xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/pages"75-83"xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/pages"75-83"xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/title"A role for transcriptional repressors in targeting the yeast Swi/Snf complex."xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/title"A role for transcriptional repressors in targeting the yeast Swi/Snf complex."xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/volume"4"xsd:string
http://purl.uniprot.org/citations/10445029http://purl.uniprot.org/core/volume"4"xsd:string