| http://purl.uniprot.org/citations/10467092 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10467092 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10467092 | http://www.w3.org/2000/01/rdf-schema#comment | "The structure of calcium-bound calmodulin (Ca2+/CaM) complexed with a 26-residue peptide, corresponding to the CaM-binding domain of rat Ca2+/CaM-dependent protein kinase kinase (CaMKK), has been determined by NMR spectroscopy. In this complex, the CaMKK peptide forms a fold comprising an alpha-helix and a hairpin-like loop whose C-terminus folds back on itself. The binding orientation of this CaMKK peptide by the two CaM domains is opposite to that observed in all other CaM-target complexes determined so far. The N- and C-terminal hydrophobic pockets of Ca2+/CaM anchor Trp 444 and Phe 459 of the CaMKK peptide, respectively. This 14-residue separation between two key hydrophobic groups is also unique among previously determined CaM complexes. The present structure represents a new and distinct class of Ca2+/CaM target recognition that may be shared by other Ca2+/CaM-stimulated proteins."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.org/dc/terms/identifier | "doi:10.1038/12271"xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.org/dc/terms/identifier | "doi:10.1038/12271"xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Furuya T."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Furuya T."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Ikura M."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Ikura M."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Kurihara H."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Kurihara H."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Osawa M."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Osawa M."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Tokumitsu H."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Tokumitsu H."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Swindells M.B."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Swindells M.B."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Orita M."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Orita M."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Shibanuma T."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/author | "Shibanuma T."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/name | "Nat. Struct. Biol."xsd:string |
| http://purl.uniprot.org/citations/10467092 | http://purl.uniprot.org/core/name | "Nat. Struct. Biol."xsd:string |