| http://purl.uniprot.org/citations/10481911 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10481911 | http://www.w3.org/2000/01/rdf-schema#comment | "To investigate mechanisms in the pathogenesis of cardiomyopathy associated with mutations of the dystrophin-glycoprotein complex, we analyzed genetically engineered mice deficient for either alpha-sarcoglycan (Sgca) or delta-sarcoglycan (Sgcd). We found that only Sgcd null mice developed cardiomyopathy with focal areas of necrosis as the histological hallmark in cardiac and skeletal muscle. Absence of the sarcoglycan-sarcospan (SG-SSPN) complex in skeletal and cardiac membranes was observed in both animal models. Loss of vascular smooth muscle SG-SSPN complex was only detected in Sgcd null mice and associated with irregularities of the coronary vasculature. Administration of a vascular smooth muscle relaxant prevented onset of myocardial necrosis. Our data indicate that disruption of the SG-SSPN complex in vascular smooth muscle perturbs vascular function, which initiates cardiomyopathy and exacerbates muscular dystrophy."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)81975-3"xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/author | "Hill J.A."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/author | "Moore S.A."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/author | "Williamson R."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/author | "Campbell K.P."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/author | "Straub V."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/author | "Weiss R.M."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/author | "Barresi R."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/author | "Cohn R.D."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/author | "Hrstka R.F."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/author | "Bansal D."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/author | "Coral-Vazquez R."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/author | "Davisson R.L."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/pages | "465-474"xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/title | "Disruption of the sarcoglycan-sarcospan complex in vascular smooth muscle: a novel mechanism for cardiomyopathy and muscular dystrophy."xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://purl.uniprot.org/core/volume | "98"xsd:string |
| http://purl.uniprot.org/citations/10481911 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10481911 |
| http://purl.uniprot.org/citations/10481911 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10481911 |
| http://purl.uniprot.org/uniprot/Q62165#attribution-D96E3616A7366136AB48CAB993D5B87F | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10481911 |
| http://purl.uniprot.org/uniprot/P82349#attribution-D96E3616A7366136AB48CAB993D5B87F | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10481911 |
| http://purl.uniprot.org/uniprot/P82350#attribution-D96E3616A7366136AB48CAB993D5B87F | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10481911 |