http://purl.uniprot.org/citations/10485890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10485890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10485890 | http://www.w3.org/2000/01/rdf-schema#comment | "A subclass of zinc finger proteins containing a unique protein motif called the positive regulatory (PR) domain has been described. The members include the PRDI-BF1/Blimp-1 protein, the Caenorhabditis elegans egl-43 and EVI1 gene products, and the retinoblastoma interacting protein RIZ. Here we describe a member of this family, SC-1, that exhibits several distinctive features. First, SC-1 interacts with the p75 neurotrophin receptor and is redistributed from the cytoplasm to the nucleus after nerve growth factor (NGF) treatment of transfected COS cells. The translocation of SC-1 to the nucleus was specific for p75, as NGF binding to the TrkA receptor did not lead to nuclear localization of SC-1. Thus, SC-1 provides a downstream transducer for the effects of NGF through the p75 neurotrophin receptor. Under normal growth conditions, SC-1 was found predominantly in the cytoplasm. On serum-starvation, SC-1 also translocated into the nucleus. A direct correlation between nuclear expression of SC-1 with the loss of BrdUrd incorporation was observed. These results imply that SC-1 may be involved in events associated with growth arrest."xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.96.19.10705"xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.96.19.10705"xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/author | "Chao M.V."xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/author | "Chao M.V."xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/author | "Chittka A."xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/author | "Chittka A."xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/pages | "10705-10710"xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/pages | "10705-10710"xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/title | "Identification of a zinc finger protein whose subcellular distribution is regulated by serum and nerve growth factor."xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/title | "Identification of a zinc finger protein whose subcellular distribution is regulated by serum and nerve growth factor."xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/volume | "96"xsd:string |
http://purl.uniprot.org/citations/10485890 | http://purl.uniprot.org/core/volume | "96"xsd:string |
http://purl.uniprot.org/citations/10485890 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10485890 |
http://purl.uniprot.org/citations/10485890 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10485890 |
http://purl.uniprot.org/citations/10485890 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10485890 |
http://purl.uniprot.org/citations/10485890 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10485890 |
http://purl.uniprot.org/uniprot/Q9QZP2 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/10485890 |
http://purl.uniprot.org/uniprot/Q9QZP2#attribution-10DACD273FF55F4525F042CE54F1B258 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10485890 |