http://purl.uniprot.org/citations/10512681 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10512681 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10512681 | http://www.w3.org/2000/01/rdf-schema#comment | "TIAM1 is a guanine nucleotide exchange factor that was identified in a screen for genes that increase the invasiveness of T lymphoma cell lines (Habets et al., 1994, Cell 77(4): 537-549). We have identified a gene, T-cell lymphoma invasion and metastasis 2 (HGMW-approved symbol TIAM2), with significant identity to the carboxyl-terminal region of the TIAM1 and mapped it to 6q25. TIAM2 is expressed as an approximately 3.3-kb transcript in cerebrum and as an approximately 4.4-kb transcript in the cerebellum and testis. The approximately 4. 4-kb message encodes a longer form of the approximately 3.3-kb mRNA predicted protein, and both contain homology to the Dbl-homologous region (70%) and Pleckstrin-homologous (54%) regions of TIAM1. We have purified TIAM2 and shown it to have GDP-GTP exchange activity. In situ hybridizations demonstrate TIAM2 expression in the E13.5 telencephalon of mouse embryos and in the cerebral cortex, hippocampus, and ependyma of adult mouse brains."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.org/dc/terms/identifier | "doi:10.1006/geno.1999.5936"xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.org/dc/terms/identifier | "doi:10.1006/geno.1999.5936"xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/author | "Kim E."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/author | "Kim E."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/author | "Duhl D.M."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/author | "Duhl D.M."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/author | "Leng S."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/author | "Leng S."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/author | "Martin K.A."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/author | "Martin K.A."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/author | "Chiu C.-Y."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/author | "Chiu C.-Y."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/author | "Gorman S."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/author | "Gorman S."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/pages | "66-73"xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/pages | "66-73"xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/title | "Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1."xsd:string |
http://purl.uniprot.org/citations/10512681 | http://purl.uniprot.org/core/title | "Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1."xsd:string |