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http://purl.uniprot.org/citations/10514570http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10514570http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10514570http://www.w3.org/2000/01/rdf-schema#comment"We have carried out the systematic disruption of six ORFs on chromosome XV, of Saccharomyces cerevisiae using the long flanking homology technique to replace each with the KanMX cassette; we have also constructed plasmids containing replacement cassettes and cognate clones for each ORF. Disruption of three of the ORFs-YOL117w, YOL114c, and YOL112w (also known as MSB4)-does not result in any noteworthy phenotype with respect to temperature or nutritional requirements, but yol112w mutants with an additional disruption of YNL293w, which encodes a protein similar to Yol112w, exhibit a slow growth phenotype. The protein specified by YOL114c shares similarity with the human DS-1 protein. Disruption of YOL115w confers slow growth, cold sensitivity and poor sporulation; this ORF has been described elsewhere as TRF4, which encodes a topoisomerase I-related protein. Cells with disruptions of YOL111c, whose product is weakly similar to the human ubiquitin-like protein GdX, are slightly impaired in mating. Mutants disrupted for YOL072w, the predicted product of which is unrelated to any protein of known function, grow slowly, are cold-sensitive and sporulate with reduced efficiency."xsd:string
http://purl.uniprot.org/citations/10514570http://purl.org/dc/terms/identifier"doi:10.1002/(sici)1097-0061(199910)15:14<1529::aid-yea457>3.0.co;2-y"xsd:string
http://purl.uniprot.org/citations/10514570http://purl.org/dc/terms/identifier"doi:10.1002/(sici)1097-0061(199910)15:14<1529::aid-yea457>3.0.co;2-y"xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/author"Nicolas A."xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/author"Nicolas A."xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/author"Fabre F."xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/author"Fabre F."xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/author"Iwanejko L."xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/author"Iwanejko L."xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/author"Loeillet S."xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/author"Loeillet S."xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/author"Smith K.N."xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/author"Smith K.N."xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/name"Yeast"xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/name"Yeast"xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/pages"1529-1539"xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/pages"1529-1539"xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/title"Disruption and functional analysis of six ORFs on chromosome XV: YOL117w, YOL115w (TRF4), YOL114c, YOL112w (MSB4), YOL111c and YOL072w."xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/title"Disruption and functional analysis of six ORFs on chromosome XV: YOL117w, YOL115w (TRF4), YOL114c, YOL112w (MSB4), YOL111c and YOL072w."xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/volume"15"xsd:string
http://purl.uniprot.org/citations/10514570http://purl.uniprot.org/core/volume"15"xsd:string