| http://purl.uniprot.org/citations/10524237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10524237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10524237 | http://www.w3.org/2000/01/rdf-schema#comment | "Metalloproteinase-disintegrins (ADAMs) are membrane-spanning multi-domain proteins containing a zinc metalloproteinase domain and a disintegrin domain which may serve as an integrin ligand. Based on a conserved sequence within the disintegrin domain, GE(E/Q)CDCG, seven genes were isolated from a human genomic library. Two of these genes lack introns and show testis-specific expression (ADAM20 and ADAM21), while the other two genes contain introns (ADAM22 and ADAM23) and are expressed predominantly in the brain. In addition, three pseudogenes were isolated; one of which evolved from ADAM21. Human chromosomal mapping indicated that ADAM22 and ADAM23 mapped to chromosome 7q21 and 2q33, respectively, while the three pseudogenes 1-2, 3-3, and 1-32 mapped to chromosome 14q24.1, 8p23, and 14q24.1, respectively. An ancestral analysis of all known ADAMs indicates that the zinc-binding motif in the catalytic domain arose once in a common ancestor and was lost by those members lacking this motif."xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0378-1119(99)00302-9"xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0378-1119(99)00302-9"xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.org/dc/terms/identifier | "doi:10.1016/S0378-1119(99)00302-9"xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/author | "Nelson N."xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/author | "Nelson N."xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/author | "DuBose R.F."xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/author | "DuBose R.F."xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/author | "Black R.A."xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/author | "Black R.A."xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/author | "Cerretti D.P."xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/author | "Cerretti D.P."xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/author | "Poindexter K."xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/author | "Poindexter K."xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/pages | "61-70"xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/pages | "61-70"xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/title | "The identification of seven metalloproteinase-disintegrin (ADAM) genes from genomic libraries."xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/title | "The identification of seven metalloproteinase-disintegrin (ADAM) genes from genomic libraries."xsd:string |
| http://purl.uniprot.org/citations/10524237 | http://purl.uniprot.org/core/volume | "237"xsd:string |