http://purl.uniprot.org/citations/10528196 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10528196 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10528196 | http://www.w3.org/2000/01/rdf-schema#comment | "The majority of the known Ly49 family members have been isolated from either C57BL/6 (B6) or BALB/c mice. Interestingly, the anti-Ly49 Ab reactivities observed in 129/J mice are different from those of B6 mice. Furthermore, immunoprecipitation of 129/J NK cell lysates with YE1/32 and YE1/48, Abs specific for the inhibitory Ly49A in B6, resulted in detection of the activation-associated DAP12 molecule. These results indicated a need for a more detailed study of this strain. Therefore, a cloning strategy was devised to isolate Ly49 cDNAs from 129/J mice. An immunoreceptor tyrosine-based inhibitory motif-containing, Ly49D-related clone was discovered that we have named Ly49O, and one immunoreceptor tyrosine-based inhibitory motif-lacking, Ly49A-related clone was discovered that we have named Ly49P. No anti-Ly49 mAb reacted with Ly49O, whereas the molecule encoded by the Ly49P cDNA was found to react with YE1/32 and YE1/48. Ly49P was found to associate with mouse DAP12, and Ab-mediated cross-linking of Ly49P resulted in mouse DAP12 phosphorylation and Ca2+ mobilization, indicating that Ly49P is a competent activation receptor. Ly49P, therefore, represents a novel member of the Ly49 activating receptor subfamily."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "Anderson S.K."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "Anderson S.K."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "McVicar D.W."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "McVicar D.W."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "Taylor L.S."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "Taylor L.S."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "Makrigiannis A.P."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "Makrigiannis A.P."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "Ortaldo J.R."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "Ortaldo J.R."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "Mason L.H."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "Mason L.H."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "Gosselin P."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/author | "Gosselin P."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/name | "J. Immunol."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/pages | "4931-4938"xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/pages | "4931-4938"xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/title | "Cloning and characterization of a novel activating Ly49 closely related to Ly49A."xsd:string |
http://purl.uniprot.org/citations/10528196 | http://purl.uniprot.org/core/title | "Cloning and characterization of a novel activating Ly49 closely related to Ly49A."xsd:string |