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http://purl.uniprot.org/citations/10529595http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10529595http://www.w3.org/2000/01/rdf-schema#comment"We analyzed the biological activities of recombinant rat interleukin-5 (IL-5). Purified recombinant rat IL-5 promoted the proliferation of T88-M cells in a concentration-dependent manner, and its effect was inhibited by an anti-murine IL-5-neutralizing polyclonal antibody. When bone marrow cells from normal rats were incubated with recombinant rat IL-5 in medium containing methylcellulose, the colony formation by eosinophilic cells was induced. Furthermore, when rat peritoneal eosinophils were incubated with recombinant rat IL-5, the spontaneous decrease in eosinophil viability was inhibited in a time- and concentration-dependent manner. In addition, the recombinant rat IL-5-induced eosinophil survival was inhibited by an anti-murine IL-5-neutralizing polyclonal antibody. These findings suggest that rat IL-5 acts as B cell growth factor II, eosinophil differentiation factor, and eosinophil survival-enhancing factor."xsd:string
http://purl.uniprot.org/citations/10529595http://purl.org/dc/terms/identifier"doi:10.1159/000053585"xsd:string
http://purl.uniprot.org/citations/10529595http://purl.uniprot.org/core/author"Ishihara K."xsd:string
http://purl.uniprot.org/citations/10529595http://purl.uniprot.org/core/author"Satoh I."xsd:string
http://purl.uniprot.org/citations/10529595http://purl.uniprot.org/core/author"Ohuchi K."xsd:string
http://purl.uniprot.org/citations/10529595http://purl.uniprot.org/core/author"Nittoh T."xsd:string
http://purl.uniprot.org/citations/10529595http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10529595http://purl.uniprot.org/core/name"Int Arch Allergy Immunol 120 Suppl"xsd:string
http://purl.uniprot.org/citations/10529595http://purl.uniprot.org/core/pages"11-14"xsd:string
http://purl.uniprot.org/citations/10529595http://purl.uniprot.org/core/title"Analysis of biological activities of recombinant rat interleukin-5."xsd:string
http://purl.uniprot.org/citations/10529595http://purl.uniprot.org/core/volume"1"xsd:string
http://purl.uniprot.org/citations/10529595http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10529595
http://purl.uniprot.org/citations/10529595http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10529595
http://purl.uniprot.org/uniprot/Q08125#attribution-84C1C1E08F69B5C1CF3009671289944Fhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/10529595
http://purl.uniprot.org/uniprot/#_Q08125-mappedCitation-10529595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10529595
http://purl.uniprot.org/uniprot/#_Q9R2C9-mappedCitation-10529595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10529595
http://purl.uniprot.org/uniprot/Q08125http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/10529595
http://purl.uniprot.org/uniprot/Q9R2C9http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/10529595