| http://purl.uniprot.org/citations/10548487 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10548487 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10548487 | http://www.w3.org/2000/01/rdf-schema#comment | "Synaptic scaffolding molecule (S-SCAM) has six PDZ domains through which it interacts with N-methyl-d-aspartate receptors and neuroligin at synaptic junctions. We isolated here a novel S-SCAM-binding protein. This protein has one PDZ, one Ras association, one Ras GDP/GTP exchange protein (Ras GEP) domain, and one C-terminal consensus motif for binding to PDZ domains. We named it nRap GEP (neural Rap GEP). nRap GEP moreover has an incomplete cyclic AMP (cAMP)-binding (CAB) domain. The domain organization of nRap GEP is similar to that of Epac/cAMP-guanine nucleotide exchange factor (GEF) I, except that Epac/cAMP-GEFI has complete CAB and Ras GEP domains but lacks the other two domains and the C-terminal motif. nRap GEP showed GEP activity for Rap1 but did not bind cAMP. nRap GEP was specifically expressed in rat brain. Immunohistochemical analysis revealed that nRap GEP and S-SCAM were localized at synaptic areas of the cerebellum. These results suggest that nRap GEP is a novel neural Rap1-specific GEP which is associated with S-SCAM."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1999.1619"xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1999.1619"xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Hata Y."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Hata Y."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Inoue T."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Inoue T."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Takai Y."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Takai Y."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Yasuda T."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Yasuda T."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Inoue E."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Inoue E."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Mizoguchi A."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Mizoguchi A."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Ohtsuka T."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Ohtsuka T."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Ide N."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/author | "Ide N."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/10548487 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |