http://purl.uniprot.org/citations/10559985 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10559985 | http://www.w3.org/2000/01/rdf-schema#comment | "Cyclin-dependent kinases (CDKs) activate the firing of replication origins during the S phase of the cell cycle. They also block re-initiation of DNA replication within a single cell cycle, by preventing the assembly of prereplicative complexes at origins. We show here that, in budding yeast, CDKs exclude the essential prereplicative-complex component Mcm4 from the nucleus. Although origin firing can be triggered by the B-type cyclins only, both G1-phase and B-type cyclins cause exit of Mcm4 from the nucleus. These results suggest that G1 cyclins may diminish the cell's capacity to assemble prereplicative complexes before B-type cyclins trigger origin firing during S phase."xsd:string |
http://purl.uniprot.org/citations/10559985 | http://purl.org/dc/terms/identifier | "doi:10.1038/15649"xsd:string |
http://purl.uniprot.org/citations/10559985 | http://purl.uniprot.org/core/author | "Labib K."xsd:string |
http://purl.uniprot.org/citations/10559985 | http://purl.uniprot.org/core/author | "Diffley J.F."xsd:string |
http://purl.uniprot.org/citations/10559985 | http://purl.uniprot.org/core/author | "Kearsey S.E."xsd:string |
http://purl.uniprot.org/citations/10559985 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10559985 | http://purl.uniprot.org/core/name | "Nat Cell Biol"xsd:string |
http://purl.uniprot.org/citations/10559985 | http://purl.uniprot.org/core/pages | "415-422"xsd:string |
http://purl.uniprot.org/citations/10559985 | http://purl.uniprot.org/core/title | "G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus."xsd:string |
http://purl.uniprot.org/citations/10559985 | http://purl.uniprot.org/core/volume | "1"xsd:string |
http://purl.uniprot.org/citations/10559985 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10559985 |
http://purl.uniprot.org/citations/10559985 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10559985 |
http://purl.uniprot.org/uniprot/P30665#attribution-705CDE8C36655F455754E9462FAF380C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/10559985 |
http://purl.uniprot.org/uniprot/#_P00546-mappedCitation-10559985 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10559985 |
http://purl.uniprot.org/uniprot/#_P30665-mappedCitation-10559985 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10559985 |
http://purl.uniprot.org/uniprot/P30665 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/10559985 |
http://purl.uniprot.org/uniprot/P00546 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/10559985 |