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http://purl.uniprot.org/citations/10559985http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10559985http://www.w3.org/2000/01/rdf-schema#comment"Cyclin-dependent kinases (CDKs) activate the firing of replication origins during the S phase of the cell cycle. They also block re-initiation of DNA replication within a single cell cycle, by preventing the assembly of prereplicative complexes at origins. We show here that, in budding yeast, CDKs exclude the essential prereplicative-complex component Mcm4 from the nucleus. Although origin firing can be triggered by the B-type cyclins only, both G1-phase and B-type cyclins cause exit of Mcm4 from the nucleus. These results suggest that G1 cyclins may diminish the cell's capacity to assemble prereplicative complexes before B-type cyclins trigger origin firing during S phase."xsd:string
http://purl.uniprot.org/citations/10559985http://purl.org/dc/terms/identifier"doi:10.1038/15649"xsd:string
http://purl.uniprot.org/citations/10559985http://purl.uniprot.org/core/author"Labib K."xsd:string
http://purl.uniprot.org/citations/10559985http://purl.uniprot.org/core/author"Diffley J.F."xsd:string
http://purl.uniprot.org/citations/10559985http://purl.uniprot.org/core/author"Kearsey S.E."xsd:string
http://purl.uniprot.org/citations/10559985http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10559985http://purl.uniprot.org/core/name"Nat Cell Biol"xsd:string
http://purl.uniprot.org/citations/10559985http://purl.uniprot.org/core/pages"415-422"xsd:string
http://purl.uniprot.org/citations/10559985http://purl.uniprot.org/core/title"G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus."xsd:string
http://purl.uniprot.org/citations/10559985http://purl.uniprot.org/core/volume"1"xsd:string
http://purl.uniprot.org/citations/10559985http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10559985
http://purl.uniprot.org/citations/10559985http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10559985
http://purl.uniprot.org/uniprot/P30665#attribution-705CDE8C36655F455754E9462FAF380Chttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/10559985
http://purl.uniprot.org/uniprot/#_P00546-mappedCitation-10559985http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10559985
http://purl.uniprot.org/uniprot/#_P30665-mappedCitation-10559985http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10559985
http://purl.uniprot.org/uniprot/P30665http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/10559985
http://purl.uniprot.org/uniprot/P00546http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/10559985