| http://purl.uniprot.org/citations/10562278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10562278 | http://www.w3.org/2000/01/rdf-schema#comment | "We visualized a fluorescent-protein (FP) fusion to Rab6, a Golgi-associated GTPase, in conjunction with fluorescent secretory pathway markers. FP-Rab6 defined highly dynamic transport carriers (TCs) translocating from the Golgi to the cell periphery. FP-Rab6 TCs specifically accumulated a retrograde cargo, the wild-type Shiga toxin B-fragment (STB), during STB transport from the Golgi to the endoplasmic reticulum (ER). FP-Rab6 TCs associated intimately with the ER, and STB entered the ER via specialized peripheral regions that accumulated FP-Rab6. Microinjection of antibodies that block coatomer protein I (COPI) function inhibited trafficking of a KDEL-receptor FP-fusion, but not FP-Rab6. Additionally, markers of COPI-dependent recycling were excluded from FP-Rab6/STB TCs. Overexpression of Rab6:GDP (T27N mutant) using T7 vaccinia inhibited toxicity of Shiga holotoxin, but did not alter STB transport to the Golgi or Golgi morphology. Taken together, our results indicate Rab6 regulates a novel Golgi to ER transport pathway."xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.147.4.743"xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/author | "Girod A."xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/author | "White J."xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/author | "Keller P."xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/author | "Echard A."xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/author | "Goud B."xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/author | "Grill S."xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/author | "Johannes L."xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/author | "Reinsch S."xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/author | "Stelzer E.H."xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/author | "Mallard F."xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/author | "Tzschaschel B."xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/name | "J Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/pages | "743-760"xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/title | "Rab6 coordinates a novel Golgi to ER retrograde transport pathway in live cells."xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://purl.uniprot.org/core/volume | "147"xsd:string |
| http://purl.uniprot.org/citations/10562278 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10562278 |
| http://purl.uniprot.org/citations/10562278 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10562278 |
| http://purl.uniprot.org/uniprot/#_P52907-mappedCitation-10562278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10562278 |
| http://purl.uniprot.org/uniprot/#_Q14203-mappedCitation-10562278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10562278 |
| http://purl.uniprot.org/uniprot/#_Q14204-mappedCitation-10562278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10562278 |
| http://purl.uniprot.org/uniprot/#_Q15042-mappedCitation-10562278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10562278 |