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http://purl.uniprot.org/citations/10570964http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10570964http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10570964http://www.w3.org/2000/01/rdf-schema#comment"Endothelial protein C receptor (EPCR), present on endothelial cells of relatively large veins and arteries, plays a role in the enhancement of protein C activation by the thrombin-thrombomodulin complex. In the present study, we determined the organization and the complete nucleotide sequence of the human EPCR gene using polymerase chain reaction-direct sequencing method. The transcription initiation site of the EPCR gene was also determined by the cap site hunting method, using a cap site cDNA prepared from human placenta. The human EPCR gene spanned approx. 6 kb and was composed of four exons and three introns. All exon-intron boundaries agreed with the GT-AG rule. The 5'-flanking region (300 bp) of the EPCR gene contained a putative AP1-binding site, two Sp1-binding sites and two AP2-binding sites, but not definite TATAA or CCAAT sequences. Fluorescence in situ hybridization analysis showed that the EPCR gene is located in chromosome 20q11.2."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.org/dc/terms/identifier"doi:10.1016/s0378-1119(99)00360-1"xsd:string
http://purl.uniprot.org/citations/10570964http://purl.org/dc/terms/identifier"doi:10.1016/s0378-1119(99)00360-1"xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Hayashi T."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Hayashi T."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Nakamura H."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Nakamura H."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Okumura K."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Okumura K."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Suzuki K."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Suzuki K."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Okada A."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Okada A."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Yuasa H."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Yuasa H."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Wakita T."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Wakita T."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Takebayashi S."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/author"Takebayashi S."xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/name"Gene"xsd:string
http://purl.uniprot.org/citations/10570964http://purl.uniprot.org/core/name"Gene"xsd:string