| http://purl.uniprot.org/citations/10573161 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10573161 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10573161 | http://www.w3.org/2000/01/rdf-schema#comment | "There is increasing evidence that hepatitis B virus (HBV) infection of an immunosuppressed host is associated with the appearance of virus mutants. To characterize the virus circulating in patients in detail, eleven full-length HBV genomes, isolated from the serum of five highly viraemic renal transplant recipients with liver disease, were cloned and sequenced. The genomes contained deletions in the C gene, deletions in the pre-S1/2 region frequently removing the pre-S2 initiation codon, premature termination codons in the pre-S1 or S region, and/or deletions/insertions in the X gene/core promoter. The mutations occurred at different positions and in various combinations; even mutant genomes circulating within a patient differed strikingly. It is concluded that long-term immunosuppression is associated with the occurrence of heterogeneous populations of partially defective HBV characterized by a specific mutation pattern. Efficient intracellular trans-complementation probably enables high virus replication in vivo."xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.org/dc/terms/identifier | "doi:10.1099/0022-1317-80-10-2685"xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/author | "Gunther S."xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/author | "Gunther S."xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/author | "Meisel H."xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/author | "Meisel H."xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/author | "Will H."xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/author | "Will H."xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/author | "Preikschat P."xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/author | "Preikschat P."xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/name | "J. Gen. Virol."xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/name | "J Gen Virol"xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/pages | "2685-2691"xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/pages | "2685-2691"xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/title | "Hepatitis B virus genomes from long-term immunosuppressed virus carriers are modified by specific mutations in several regions."xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/title | "Hepatitis B virus genomes from long-term immunosuppressed virus carriers are modified by specific mutations in several regions."xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/volume | "80"xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://purl.uniprot.org/core/volume | "80"xsd:string |
| http://purl.uniprot.org/citations/10573161 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10573161 |
| http://purl.uniprot.org/citations/10573161 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10573161 |
| http://purl.uniprot.org/citations/10573161 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10573161 |