| http://purl.uniprot.org/citations/10595929 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10595929 | http://www.w3.org/2000/01/rdf-schema#comment | "Bone wound created in intramembranous alveolar bone heals without the formation of cartilage precursor tissue. However, the expression of cartilage collagen mRNAs has been suggested. In this report, we examined the expression and the potential role of type IX collagen in bone restoration and remodeling. The sequence specific polymerase chain reaction demonstrated the exclusive expression of short transcriptional isoform of alpha1(IX) collagen (Col9a1) in alveolar bone wound healing, while the long isoform of Col9a1 transcript was absent. Type IX collagen was immunolocalized in the preliminary matrix organized in granulation tissue before trabecular bone formation in tooth extraction socket. In Col9a1-null mutant mice, there were considerable variations in alveolar bone wound healing with the absence of or abnormally organized trabecular bone. Occasionally, unusual apposition of cortical-bone-like layers in bone marrow space was observed. The Col9a1-null mice indicated no growth retardation, and their facial and long bones maintained the normal size and shape. However, the primary spongiosa region of adult Col9a1 mutant mice showed an abnormal trabecular bone structure associated with abnormal immunostaining with the hypertrophic cartilage specific type X collagen antibody. These data suggest that type IX collagen short transcriptional variant is involved in the restoration and remodeling processes of trabecular bone."xsd:string |
| http://purl.uniprot.org/citations/10595929 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0002-9440(10)65518-6"xsd:string |
| http://purl.uniprot.org/citations/10595929 | http://purl.uniprot.org/core/author | "Olsen B.R."xsd:string |
| http://purl.uniprot.org/citations/10595929 | http://purl.uniprot.org/core/author | "Nishimura I."xsd:string |
| http://purl.uniprot.org/citations/10595929 | http://purl.uniprot.org/core/author | "Ramachandran H."xsd:string |
| http://purl.uniprot.org/citations/10595929 | http://purl.uniprot.org/core/author | "Ting K."xsd:string |
| http://purl.uniprot.org/citations/10595929 | http://purl.uniprot.org/core/author | "Chung K.S."xsd:string |
| http://purl.uniprot.org/citations/10595929 | http://purl.uniprot.org/core/author | "Shah-Hosseini N."xsd:string |
| http://purl.uniprot.org/citations/10595929 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10595929 | http://purl.uniprot.org/core/name | "Am J Pathol"xsd:string |
| http://purl.uniprot.org/citations/10595929 | http://purl.uniprot.org/core/pages | "1993-1999"xsd:string |
| http://purl.uniprot.org/citations/10595929 | http://purl.uniprot.org/core/title | "A short isoform of Col9a1 supports alveolar bone repair."xsd:string |
| http://purl.uniprot.org/citations/10595929 | http://purl.uniprot.org/core/volume | "155"xsd:string |
| http://purl.uniprot.org/citations/10595929 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10595929 |
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