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http://purl.uniprot.org/citations/10601038http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10601038http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10601038http://www.w3.org/2000/01/rdf-schema#comment"Eph receptor tyrosine kinases and their corresponding surface-bound ligands, the ephrins, provide cues to the migration of cells and growth cones during embryonic development. Here we show that ephrin-A5, which is attached to the outer leaflet of the plasma membrane by a glycosyl-phosphatidylinositol-anchor, induces compartmentalized signaling within a caveolae-like membrane microdomain when bound to the extracellular domain of its cognate Eph receptor. The physiological response induced by this signaling event is concomitant with a change in the cellular architecture and adhesion of the ephrin-A5-expressing cells and requires the activity of the Fyn protein tyrosine kinase. This study stresses the relevance of bidirectional signaling involving the ephrins and Eph receptors during brain development."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.org/dc/terms/identifier"doi:10.1101/gad.13.23.3125"xsd:string
http://purl.uniprot.org/citations/10601038http://purl.org/dc/terms/identifier"doi:10.1101/gad.13.23.3125"xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Robbins S.M."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Robbins S.M."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Gale N.W."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Gale N.W."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Davy A."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Davy A."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Soriano P."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Soriano P."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Feuerstein C."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Feuerstein C."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Klinghoffer R.A."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Klinghoffer R.A."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Murray E.W."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/author"Murray E.W."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/name"Genes Dev."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/name"Genes Dev."xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/pages"3125-3135"xsd:string
http://purl.uniprot.org/citations/10601038http://purl.uniprot.org/core/pages"3125-3135"xsd:string