| http://purl.uniprot.org/citations/10618248 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10618248 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10618248 | http://www.w3.org/2000/01/rdf-schema#comment | "Sterigmatocystin (ST) and aflatoxin B(1) (AFB(1)) are two polyketide-derived Aspergillus mycotoxins synthesized by functionally identical sets of enzymes. ST, the compound produced by Aspergillus nidulans, is a late intermediate in the AFB(1) pathway of A. parasiticus and A. flavus. Previous biochemical studies predicted that five oxygenase steps are required for the formation of ST. A 60-kb ST gene cluster in A. nidulans contains five genes, stcB, stcF, stcL, stcS, and stcW, encoding putative monooxygenase activities. Prior research showed that stcL and stcS mutants accumulated versicolorins B and A, respectively. We now show that strains disrupted at stcF, encoding a P-450 monooxygenase similar to A. parasiticus avnA, accumulate averantin. Disruption of either StcB (a putative P-450 monooxygenase) or StcW (a putative flavin-requiring monooxygenase) led to the accumulation of averufin as determined by radiolabeled feeding and extraction studies."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.org/dc/terms/identifier | "doi:10.1128/aem.66.1.359-362.2000"xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.org/dc/terms/identifier | "doi:10.1128/aem.66.1.359-362.2000"xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/author | "Adams T.H."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/author | "Adams T.H."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/author | "Keller N.P."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/author | "Keller N.P."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/author | "Kelkar H.S."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/author | "Kelkar H.S."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/author | "Townsend C.A."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/author | "Townsend C.A."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/author | "Watanabe C.M."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/author | "Watanabe C.M."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/name | "Appl. Environ. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/name | "Appl. Environ. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/pages | "359-362"xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/pages | "359-362"xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/title | "Requirement of monooxygenase-mediated steps for sterigmatocystin biosynthesis by Aspergillus nidulans."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/title | "Requirement of monooxygenase-mediated steps for sterigmatocystin biosynthesis by Aspergillus nidulans."xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/volume | "66"xsd:string |
| http://purl.uniprot.org/citations/10618248 | http://purl.uniprot.org/core/volume | "66"xsd:string |