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| http://purl.uniprot.org/citations/10620707 | http://www.w3.org/2000/01/rdf-schema#comment | "The influence of anisoosmolarity on NF-kappaB binding activity was studied in H4IIE rat hepatoma cells. Hypoosmolarity induced a sustained NF-kappaB binding activity whereas the hyperosmotic NF-kappaB response was only minor. Hypoosmotic NF-kappaB activation was accompanied by degradation of the inhibitory IkappaB-alpha. Protein kinase C, PI(3)-kinase, reactive oxygen intermediates and the proteasome apparently participate in mediating the hypoosmotic effect on NF-kappaB. Hypoosmolarity plus PMA induced, amplified and prolonged IkappaB-alpha degradation and NF-kappaB binding activity. Transforming growth factor beta-induced apoptosis was diminished by hypoosmolarity. However, this anti-apoptotic effect was probably not related to NF-kappaB activation."xsd:string |
| http://purl.uniprot.org/citations/10620707 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(99)01719-6"xsd:string |
| http://purl.uniprot.org/citations/10620707 | http://purl.uniprot.org/core/author | "Schliess F."xsd:string |
| http://purl.uniprot.org/citations/10620707 | http://purl.uniprot.org/core/author | "Haussinger D."xsd:string |
| http://purl.uniprot.org/citations/10620707 | http://purl.uniprot.org/core/author | "Michalke M."xsd:string |
| http://purl.uniprot.org/citations/10620707 | http://purl.uniprot.org/core/author | "Cariers A."xsd:string |
| http://purl.uniprot.org/citations/10620707 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10620707 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/10620707 | http://purl.uniprot.org/core/pages | "64-68"xsd:string |
| http://purl.uniprot.org/citations/10620707 | http://purl.uniprot.org/core/title | "Hypoosmolarity influences the activity of transcription factor NF-kappaB in rat H4IIE hepatoma cells."xsd:string |
| http://purl.uniprot.org/citations/10620707 | http://purl.uniprot.org/core/volume | "465"xsd:string |
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