| http://purl.uniprot.org/citations/10625422 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10625422 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10625422 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
| http://purl.uniprot.org/citations/10625422 | http://www.w3.org/2000/01/rdf-schema#comment | "Pseudouridine synthases catalyze the isomerization of specific uridines to pseudouridine in a variety of RNAs, yet the basis for recognition of the RNA sites or how they catalyze this reaction is unknown. The crystal structure of pseudouridine synthase I from Escherichia coli, which, for example, modifies positions 38, 39 and/or 40 in tRNA, reveals a dimeric protein that contains two positively charged, RNA-binding clefts along the surface of the protein. Each cleft contains a highly conserved aspartic acid located at its center. The structural domains have a topological similarity to those of other RNA-binding proteins, though the mode of interaction with tRNA appears to be unique. The structure suggests that a dimeric enzyme is required for binding transfer RNA and subsequent pseudouridine formation."xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.org/dc/terms/identifier | "doi:10.1038/71219"xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.org/dc/terms/identifier | "doi:10.1038/71219"xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/author | "Huang L."xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/author | "Huang L."xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/author | "Stroud R.M."xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/author | "Stroud R.M."xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/author | "Foster P.G."xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/author | "Foster P.G."xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/author | "Santi D.V."xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/author | "Santi D.V."xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/name | "Nat. Struct. Biol."xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/name | "Nat. Struct. Biol."xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/pages | "23-27"xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/pages | "23-27"xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/title | "The structural basis for tRNA recognition and pseudouridine formation by pseudouridine synthase I."xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/title | "The structural basis for tRNA recognition and pseudouridine formation by pseudouridine synthase I."xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/volume | "7"xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://purl.uniprot.org/core/volume | "7"xsd:string |
| http://purl.uniprot.org/citations/10625422 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10625422 |