| http://purl.uniprot.org/citations/10625619 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10625619 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10625619 | http://www.w3.org/2000/01/rdf-schema#comment | "We describe the characterization of siglec-8, a novel sialic acid-binding immunoglobulin-like lectin that is expressed specifically by eosinophils. A full-length cDNA encoding siglec-8 was isolated from a human eosinophil cDNA library. Siglec-8 is predicted to contain three extracellular immunoglobulin-like domains, a transmembrane region, and a cytoplasmic tail of 47 amino acids. The siglec-8 gene mapped on chromosome 19q13.33-41, closely linked to genes encoding CD33 (siglec-3), siglec-5, siglec-6, and siglec-7. When siglec-8 was expressed on COS cells or as a recombinant protein fused to the Fc region of human IgG(1), it was able to mediate sialic acid-dependent binding to human erythrocytes and to soluble sialoglycoconjugates. Using specific monoclonal antibodies, siglec-8 could be detected only on eosinophils and hence appears to be the first example of an eosinophil-specific transmembrane receptor."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.275.2.861"xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.275.2.861"xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Liu D."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Liu D."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Ni J."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Ni J."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Zeng Z."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Zeng Z."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Crocker P.R."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Crocker P.R."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Carter K.C."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Carter K.C."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Steel J."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Steel J."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Floyd H."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Floyd H."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Cornish A.L."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/author | "Cornish A.L."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/10625619 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |