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http://purl.uniprot.org/citations/10648820http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10648820http://www.w3.org/2000/01/rdf-schema#comment"Tyrosine phosphorylation of Cbl and its association with signal-transducing molecules in response to macrophage colony-stimulating factor (M-CSF) were analyzed by using cell lines which express the wild-type and a mutant M-CSF receptor, Fms. We found that in a clone, F723 TF-1 cells expressing mutant Fms in which tyrosine 723 had been substituted with phenylalanine, the M-CSF stimulation-dependent association between Cbl and Fms was markedly impaired. However, phosphorylation of Cbl and its association with the p85 subunit of phosphatidylinositol 3-kinase were induced in these mutant cells as seen in the wild-type fms transfectant. These results suggest that phosphorylation of tyrosine 723 is particularly important for the recruitment of Cbl to the M-CSF receptor, but is not required for the phosphorylation and binding of Cbl to signal-transducing molecules such as p85."xsd:string
http://purl.uniprot.org/citations/10648820http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(99)01767-6"xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/author"Nakamura Y."xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/author"Shimamura S."xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/author"Sato K."xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/author"Yamada M."xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/author"Suzu S."xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/author"Nagata N."xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/author"Motoyoshi K."xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/author"Kimura F."xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/author"Wakimoto N."xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/author"Ota J."xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/name"FEBS Lett"xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/pages"96-100"xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/title"Association of Cbl with Fms and p85 in response to macrophage colony-stimulating factor."xsd:string
http://purl.uniprot.org/citations/10648820http://purl.uniprot.org/core/volume"466"xsd:string
http://purl.uniprot.org/citations/10648820http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10648820
http://purl.uniprot.org/citations/10648820http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10648820
http://purl.uniprot.org/uniprot/#_P42224-mappedCitation-10648820http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10648820
http://purl.uniprot.org/uniprot/#_P06241-mappedCitation-10648820http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10648820
http://purl.uniprot.org/uniprot/#_P27986-mappedCitation-10648820http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10648820
http://purl.uniprot.org/uniprot/#_O75791-mappedCitation-10648820http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10648820
http://purl.uniprot.org/uniprot/#_P42338-mappedCitation-10648820http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10648820