| http://purl.uniprot.org/citations/10657125 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10657125 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10657125 | http://www.w3.org/2000/01/rdf-schema#comment | "The SCL gene encodes a highly conserved bHLH transcription factor with a pivotal role in hemopoiesis and vasculogenesis. We have sequenced and analyzed 320 kb of genomic DNA composing the SCL loci from human, mouse, and chicken. Long-range sequence comparisons demonstrated multiple peaks of human/mouse homology, a subset of which corresponded precisely with known SCL enhancers. Comparisons between mammalian and chicken sequences identified some, but not all, SCL enhancers. Moreover, one peak of human/mouse homology (+23 region), which did not correspond to a known enhancer, showed significant homology to an analogous region of the chicken SCL locus. A transgenic Xenopus reporter assay was established and demonstrated that the +23 region contained a new neural enhancer. This combination of long-range comparative sequence analysis with a high-throughput transgenic bioassay provides a powerful strategy for identifying and characterizing developmentally important enhancers."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.org/dc/terms/identifier | "doi:10.1038/72635"xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.org/dc/terms/identifier | "doi:10.1038/72635"xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Bentley D.R."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Bentley D.R."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "McMurray A."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "McMurray A."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Mistry S."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Mistry S."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Vaudin M."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Vaudin M."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Grafham D."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Grafham D."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Green A.R."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Green A.R."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Gilbert J.R."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Amaya E."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Amaya E."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Gottgens B."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Gottgens B."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Bahn S."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Bahn S."xsd:string |
| http://purl.uniprot.org/citations/10657125 | http://purl.uniprot.org/core/author | "Barton L.M."xsd:string |