| http://purl.uniprot.org/citations/10665499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10665499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10665499 | http://www.w3.org/2000/01/rdf-schema#comment | "A novel missense mutation, Leu723Pro, in the amyloid precursor protein (APP) gene was discovered in an early-onset Alzheimer's disease family. Expression of L723P mutant APP complementary DNA in CHO cells resulted in a 1.4-to 1.9-fold increased production of the 42(43)-amino acid length amyloid beta peptide compared with the wild-type sequence and was capable of causing apoptosis. The mutation is predicted to alter the luminal transmembrane length and helical arrangement of the APP molecule and thus affect the gamma-secretase cleavage site."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.org/dc/terms/identifier | "doi:10.1002/1531-8249(200002)47:2<249::aid-ana18>3.0.co;2-8"xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.org/dc/terms/identifier | "doi:10.1002/1531-8249(200002)47:2<249::aid-ana18>3.0.co;2-8"xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Beyreuther K."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Beyreuther K."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Li Q.X."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Li Q.X."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Ames D."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Ames D."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Hallupp M."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Hallupp M."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Schofield P.R."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Schofield P.R."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Kwok J.B.J."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Kwok J.B.J."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Masters C.L."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Masters C.L."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Whyte S."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/author | "Whyte S."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/name | "Ann. Neurol."xsd:string |
| http://purl.uniprot.org/citations/10665499 | http://purl.uniprot.org/core/name | "Ann. Neurol."xsd:string |