| http://purl.uniprot.org/citations/10681538 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10681538 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10681538 | http://www.w3.org/2000/01/rdf-schema#comment | "The formation of triple helical DNA has been evoked in several cellular processes including transcription, replication, and recombination. Using conventional and affinity chromatography, we purified from Saccharomyces cerevisiae whole-cell extract a 35-kDa protein that avidly and specifically bound a purine motif triplex (with a K(d) of 61 pM) but not a pyrimidine motif triplex or duplex DNA. Peptide microsequencing identified this protein as the product of the STM1 gene. Confirmation that Stm1p is a purine motif triplex-binding protein was obtained by electrophoretic mobility shift assays using either bacterially expressed, recombinant Stm1p or whole-cell extracts from stm1Delta yeast. Stm1p has previously been identified as G4p2, a G-quartet nucleic acid-binding protein. This suggests that some proteins actually recognize features shared by G4 DNA and purine motif triplexes, e.g. Hoogsteen hydrogen-bonded guanines. Genetically, the STM1 gene has been identified as a multicopy suppressor of mutations in several genes involved in mitosis (e.g. TOM1, MPT5, and POP2). A possible role for multiplex DNA and its binding proteins in mitosis is discussed."xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.275.8.5573"xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.275.8.5573"xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/author | "Van Dyke M.W."xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/author | "Van Dyke M.W."xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/author | "Musso M."xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/author | "Musso M."xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/author | "Nelson L.D."xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/author | "Nelson L.D."xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/pages | "5573-5581"xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/pages | "5573-5581"xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/title | "The yeast STM1 gene encodes a purine motif triple helical DNA-binding protein."xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/title | "The yeast STM1 gene encodes a purine motif triple helical DNA-binding protein."xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/volume | "275"xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://purl.uniprot.org/core/volume | "275"xsd:string |
| http://purl.uniprot.org/citations/10681538 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10681538 |
| http://purl.uniprot.org/citations/10681538 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10681538 |
| http://purl.uniprot.org/citations/10681538 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10681538 |
| http://purl.uniprot.org/citations/10681538 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10681538 |